Scientific discoveries this week: 4/22/13
San Francisco, California
Scientists from UC San Francisco discovered that muscle repair requires the action of two types of cells known for causing inflammation and forming fat. The finding found that a immune cell called the eosinophil carries out muscle repair by clearing out cellular debris from damaged tissue and teaming up with a type of cell that can make fat to instead trigger muscle regrowth. The eosinophils move to the site of the injury and collaborate with a progenitor cell–an immature cell similar to stem cells to form new muscle fibers.The progenitor cells are well known for their role in making fat which occurs when the body experiences prolonged immobility. Eosinophils are known for fighting bacteria and parasites, like other immune cells, but they are more often thought of for their role in allergic reactions and other inflammatory reactions. The researchers are trying to determine if eosinophils and the progenitor cells are universally employed in injuries sites as a way to get rid of debris and rebuilding muscle without triggering anaphylactic shock.